An increasing number of people are asking about using our assembly approaches for things that we haven't yet written (or posted) papers about. Moreover, our assembly strategies themselves are also under constant evolution as we do more research and find ever-wider applicability of our approaches.
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At BOSC 2012, we heard a report from Richard Holland on the Pistoia Alliance Sequence Squeeze competition. I'd run across this a couple of times before -- most notably in the Quip paper -- and was interested in hearing the results.
What was the problem being tackled? To quote,
read moreThe volume of …
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One of my favorite in-class exercises is The Assembly Exercise, in which I provided "shotgun sequence" from some English text and ask the students to assemble it. Normally I provide a printout of about 10-20 pages of reads with range of read lengths, error rates, and single/paired end sequences …
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The IPython Notebook (or 'ipynb' for short) is one of the most exciting technologies for teaching and research that I've seen in recent years. It is a completely open source, well architected, and fairly stable system for scientific computing and data exploration.
I've now been using it for teaching for …
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We held the 2012 workshop on Analyzing Next Generation Sequencing Data from June 4 to June 15, at the Kellogg Biological Station in western Michigan, about 30 minutes north of Kalamazoo.
(This is a long delayed blog post. :)
The goal of the workshop is to take biologists with little in …
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At our 2012 course on Analyzing Next-Generation Sequencing Data, we talked quite a bit about future sequencing technologies, as well as about what analyses are reasonably cookbook (and which ones aren't).
Here are my thoughts -- yours welcome!
The basic conclusions about sequencing tech were these:
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As part of the 2012 Analyzing Next-Generation Sequencing Data course, I've been trying out ipython notebook for the tutorials.
In previous years, our tutorials all looked like this: Short read assembly with Velvet -- basically, reStructuredText files integrated with Sphinx. This had a lot of advantages, including Googleability and simplicity; but …
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