1. A memory efficient way to remove low-abundance k-mers from large (metagenomic?) DNA data sets

    I've spent the last few weeks working on a simple solution to a challenging problem in DNA sequence assembly, and I think we've got a nice simple theoretical solution with an actual implementation. I'd be interested in comments!

    Introduction

    Briefly, the algorithmic challenge is this:

    We have a bunch of …

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  2. Teaching next-gen sequencing data analysis to biologists

    Our sequencing analysis course ended last Friday, with an overwhelmingly positive response from the students. The few negative comments that I got were largely about organizational issues, and could be reshaped as suggestions for next time rather than as condemnations of this year's course.

    The 23 students -- most with no …

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