Here's a data analysis question for all you Big Data folk.
A beachcomber is interested in obtaining up to 10 examples of every type of shell present on a beach. The shells are individually easy to find, but some types are really rare and some are really abundant. The beachcomber …
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(Or, "A better way to publish bioinformatics.")
We just got word that our paper, "Scaling metagenome assembly with probabilistic de Bruijn graphs" [ arXiv ] [ github ] has been accepted for publication in PNAS. (Yay!) I just posted the final version to github, and the arXiv PDF should be updated to the third …
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At our 2012 course on Analyzing Next-Generation Sequencing Data, we talked quite a bit about future sequencing technologies, as well as about what analyses are reasonably cookbook (and which ones aren't).
Here are my thoughts -- yours welcome!
The basic conclusions about sequencing tech were these:
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I've just moved my blog over to Pelican, a static blog generator that takes in reStructuredText and spits out, well, this! I'm now using Disqus for commenting, too.
The main motivations for the move (apart from slightly better theming) were to escape dynamic-blog-land in favor of static-blog-land, while enabling a …
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About a year ago, I came across a really interesting Science paper entitled "Rapid and inefficient isolation of single cells from soil". In it, the authors -- from a well-known lab at UC Davis -- described how they used low-percentage agarose gels to extract thousands of individual cells from a soil sample …
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As part of the 2012 Analyzing Next-Generation Sequencing Data course, I've been trying out ipython notebook for the tutorials.
In previous years, our tutorials all looked like this: Short read assembly with Velvet -- basically, reStructuredText files integrated with Sphinx. This had a lot of advantages, including Googleability and simplicity; but …
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I just returned from a NESCent Catalysis meeting on Cephalopod Genomics. I was invited as a bioinformatics and genomics guy, and so I spent four days in North Carolina talking about the opportunities and challenges of sequencing cephalopods.
Cephalopods are a class of the molluscs, and include squid and octopus …
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